Stevioside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Stevioside 是从甜叶菊叶中提取的一种天然甜味剂，具有抗癌活性。

A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. Exhibits transepithelial p-aminohippurate transport via organic anion transport system interference.

Apoptosis Analysis Cell Line:MDA-MB-231 Concentration:10 μM Incubation Time:24 h Result:Increased the rate of apoptosis in cells with combination of 5-Fu (HY-90006).Increased ROS level significantly in MDA-MB-231. Combinated with 5-Fu (HY-90006) could trigger early and late apoptotic events in cancer cells.Western Blot AnalysisCell Line:THP-1 cells Concentration:1 mM Incubation Time:45 min Result:Inhibited the expression level of NF-κB and IKKβ.

Animal Model:Balb/c miceDosage:6.25-25 mg/kg Administration:p.o., daily, 7 days Result:Didn’t show any change in the general behaviour of the test animals.Increased antibody synthesis of 15.38% and delayed type hypersensitivity (DTH) response of 18% at the dose of 12.5 mg/kg.

Steviosin | CCRIS 6116

Others

Other Targets

TLR2

Metabolic Disease

——

57817-89-7

804.88

C38H60O18

>98% (HPLC)

DMSO: 10 mM

C=C([C@@](CC1)(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C4)C[C@@]54CC[C@]6([H])[C@@](C(O[C@H]7[C@@H]([C@H]([C@@H]([C@@H](CO)O7)O)O)O)=O)(C)CCC[C@@]6(C)[C@@]51[H]

(4alpha)-beta-D-Glucopyranosyl 13-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)kaur-16-en-18-oate

(-20℃)

With Ice Pack

≥ 2 years