Atropine sulfate ( —— )

产品货号. M15016 CAS No. 55-48-1

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Atropine sulfate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

硫酸阿托品是一种竞争性毒蕈碱乙酰胆碱受体拮抗剂。
产品描述

Atropine sulfate is a competitive muscarinic acetylcholine receptor antagonist.(In Vitro):Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) sulfate inhibits ACh-induced relaxations in human pulmonary veins.(In Vivo):Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) sulfate inhibits the cardiac arrhythmia which normally occurs throughout torpor.
体外实验

Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) sulfate inhibits ACh-induced relaxations in human pulmonary veins.
体内实验

Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) sulfate inhibits the cardiac arrhythmia which normally occurs throughout torpor. Animal Model:White-footed mice (Peromyscus sp.)Dosage:10 mg/kg Administration:Intraperitoneal injection; once, for 40 minutes Result:Increased heart rate was a decrease in cardiac arrhythmia.
同义词

——
通路

Endocrinology/Hormones
靶点

AChR
受体

mAChR
研究领域

Neurological Disease
适应症

——

CAS Number

55-48-1
分子量

676.82
分子式

2C17H23NO3·H2SO4
纯度

>98% (HPLC)
溶解度

Soluble in Water
SMILES

OS(O)(=O)=O.CN1C2CCC1CC(C2)OC(=O)C(CO)C1=CC=CC=C1.CN1C2CCC1CC(C2)OC(=O)C(CO)C1=CC=CC=C1
化学全称

——

1.Huang XP, et al. J Pharmacol Exp Ther. 1998 Sep; 286(3):1129-39.

计算器

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