Ibudilast ( AV 411 | KC-404 )

产品货号. M14741 CAS No. 50847-11-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ibudilast
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ibudilast（KC-404；AV-411；MN-166）是一种相对非选择性的磷酸二酯酶抑制剂，已上市用于治疗哮喘。
产品描述

Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.
体外实验

Western Blot Analysis Cell Line:Microglia Concentration:1~100 μM Incubation Time:24 hours Result:Suppressed both IL-1β and IL-6 production at 100 μM, and significantly suppresses TNF-α production at 10 and 100 μM. ?
体内实验

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同义词

AV 411 | KC-404
通路

Angiogenesis
靶点

PDE
受体

PDE
研究领域

Inflammation/Immunology
适应症

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1.Yamazaki T, et al. Eur J Pharmacol. 2010 Oct 29.

计算器

产品手册

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