Ethyl ferulate ( BBR 3222 | NSC 14879 )

产品货号. M14386 CAS No. 4046-02-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ethyl ferulate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

阿魏酸乙酯是从当归、川芎中提取的。
产品描述

Ethyl ferulate is extracted from angelica, Chuan Xiong.
体外实验

Western Blot Analysis Cell Line:RPE cells (induced by 150 μM CoCl2 for 12 h)Concentration:40 μM Incubation Time:2 h Result:Increased Nrf-2 expression and nuclear translocation.Decreased Keap-1 expression, Aand increased HO-1 and NQO-1 expression.Reduced hypoxia-induced HIF-1α and VEGFA expression.
体内实验

Animal Model:LPS (0.5 mg/kg)-induced acute lung injury mice model Dosage:15 and 30 mg/kg Administration:i.p., twice a day for 5 days Result:Reduced leukocyte infiltration.Reduced MPO activity, mRNA levels and secretion of TNF-α and IL-6.
同义词

BBR 3222 | NSC 14879
通路

Others
靶点

Other Targets
受体

Others
研究领域

Other Indications
适应症

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1.nazaré AC, et al. Molecules. 2014 Jun 17;19(6):8124-39.

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