• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Glucosamine

CAS No. 3416-24-8

Glucosamine ( —— )

产品货号. M14160 CAS No. 3416-24-8

氨基葡萄糖通常用作骨关节炎的治疗方法,尽管其作为药物疗法的接受程度各不相同。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥140 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥162 有现货

生物学信息

  • 产品名称
    Glucosamine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    氨基葡萄糖通常用作骨关节炎的治疗方法,尽管其作为药物疗法的接受程度各不相同。
  • 产品描述
    Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies. It is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis. (In Vitro):Glucosamine (D-Glucosamine) exhibits dose-dependent DPPH antioxidant activity.Glucosamine treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins.Glucosamine significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.
  • 体外实验
    Glucosamine (D-Glucosamine) exhibits dose-dependent DPPH antioxidant activity. Glucosamine treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins. Glucosamine significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Apoptosis
  • 靶点
    CFTR
  • 受体
    Chitosanase| MMP-9| NF-κB| IFγ| TNF-α
  • 研究领域
    Other Indications
  • 适应症
    ——

化学信息

  • CAS Number
    3416-24-8
  • 分子量
    179.17
  • 分子式
    C6H13NO5
  • 纯度
    >98% (HPLC)
  • 溶解度
    Water: 551.0 mg/mL
  • SMILES
    NC(C=O)C(O)C(O)C(O)CO
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Fenton JI, et al. Equine Vet J Suppl. 2002 Sep;(34):219-23.
产品手册
关联产品
  • UCCF-853

    UCCF-853 是 CFTR 的调节剂。

  • FDL169

    FDL-169 是一种新型有效的 CFTR(囊性纤维化跨膜电导调节剂)校正剂,用于治疗携带 F508del 突变的囊性纤维化 (CF) 患者。

  • VX-809

    VX-809 (Lumacaftor, VRT 826809) 是一种有效的 CFTR 校正剂,可增加 F508del-CFTR 介导的氯离子转运,并改善 FRT 细胞中 F508del-CFTR 的成熟,EC50 分别为 0.1 和 0.5 uM。