Chlorogenic Acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

绿原酸（NSC-407296；3-O-咖啡酰奎尼酸）是人类饮食中最丰富的多酚之一，据报道可抑制 Y 细胞生长，也是金银花提取物的主要抗炎成分。

Chlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.

——

Animal Model:Experimental reflux esophagitis (RE) in ratsDosage:10, 30, 100 mg/kg Administration:p.o.Result:Reduced esophageal lipid peroxidation (marker: MDA) and increased the reduced glutathione/oxidized glutathione ratio. Inhibited the increases in the serum level of TNF-α, and expressions of iNOS and COX-2 protein.Animal Model:LPS/GalN-challenged mice Dosage:10 mg/kg Administration:i.v.Result:Increased survival rates of LPS/GalN-intoxicated mice.Inhibited LPS/GalN-induced phosphorylation of NF-κB p65 or c-Jun, without affecting p-IRF3 levels in the liver lobules.

3-O-Caffeoylquinic acid | Heriguard | NSC 407296

Others

Other Targets

Others

Inflammation/Immunology

——

327-97-9

354.32

C16H18O9

>98% (HPLC)

Ethanol: 71 mg/mL (200.38 mM); Water: 18 mg/mL (50.8 mM); DMSO: 71 mg/mL (200.38 mM)

O=C([C@@]1(O)C[C@@H](OC(/C=C\C2=CC=C(O)C(O)=C2)=O)[C@H](O)[C@H](O)C1)O

(1S,3R,4R,5R)-3-{[(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid

(-20℃)

With Ice Pack

≥ 2 years