Carbamazepine ( Carbamazepine, Tegretol, Epitol )

产品货号. M13912 CAS No. 298-46-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Carbamazepine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

卡马西平是一种钠通道阻滞剂，是一种抗惊厥化合物。
产品描述

Carbamazepine, a?sodium channel?blocker, is an anticonvulsant drug.
体外实验

Western Blot Analysis Cell Line:3T3-L1 pre-adipocytes Concentration:0-500 μM Incubation Time:10 days Result:Decreased PPAR-γ and C/EPB-α protein levels.Increased ERK 1/2 phosphorylation after a 10?min exposure, and also increased p38 MAPK phosphorylation.
体内实验

Animal Model:70% Partial hepatectomy treated mice Dosage:250 mg/kg Administration:p.o.Result:Recoverd liver to body weight ratio.Increased the number of BrdU-positive nuclei, Increased PCNA protein.Increased mRNA levels of ccne2 and ccna2.
同义词

Carbamazepine, Tegretol, Epitol
通路

Membrane Transporter/Ion Channel
靶点

Sodium Channel
受体

Sodium Channel
研究领域

Neurological Disease
适应症

——

1.Willow M, et al. Mol Pharmacol, 1982, 22(3), 627-635.

计算器

产品手册

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