Indazole ( —— )

产品货号. M13828 CAS No. 271-44-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Indazole
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

吲唑，也称为苯并吡唑或异吲达酮，是一种杂环芳香族有机化合物。
产品描述

Indazole, also called benzpyrazole or isoindazone, is a heterocyclic aromatic organic compound. Indazole derivatives display a broad variety of biological activities.
体外实验

Indazole compounds possess potential anticancer activity, and indazole-based agents such as, Axitinib (HY-10065), Lonidamine (HY-B0486) and Pazopanib (HY-10208) have already been used for cancer research, demonstrating indazole compounds as useful templates for the development of novel anticancer agents.Indazoles show potent activities against neurological disorders by inhibiting the monoamine oxidase (MAO) and kinase enzymes like Glycogen synthase kinase 3 (GSK3), and leucinerich repeat kinase enzyme 2 (LRRK2). Various natural and synthetic indazole derivatives Nigellicine, Nigellamine, Nigellidine, Zanubrutinib (HY-101474A) and SCH772984 (HY-50846) showes prominent results to cure various gastrointestinal disorders.
体内实验

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同义词

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通路

Membrane Transporter/Ion Channel
靶点

Sodium Channel
受体

Sodium Channel
研究领域

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适应症

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1.Matsumura N, et al. Epilepsy Res. 2013 May;104(3):203-16.

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