Wiskostatin ( —— )

产品货号. M13755 CAS No. 253449-04-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Wiskostatin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Wiskott-Aldrich 综合征蛋白 (WASP) 和 WAVE 刺激肌动蛋白相关蛋白 (Arp)2/3 介导的肌动蛋白聚合，从而产生多种下游效应。
产品描述

Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization, leading to diverse downstream effects, including the formation and remodeling of cell surface protrusions, modulation of cell migration, and intracytoplasmic propulsion of organelles and pathogens. Selective inhibitors of individual Arp2/3 activators would enable more exact dissection of WASP- and WAVE-dependent cellular pathways and are potential therapeutic targets for viral pathogenesis. Wiskostatin is a recently described chemical inhibitor that selectively inhibits neuronal WASP (N-WASP)-mediated actin polymerization in vitro.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

WASP(Arp)2/3
研究领域

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适应症

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1.Guerriero CJ, Weisz OA. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1562-6.

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