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Guanabenz acetate
CAS No. 23256-50-0
Guanabenz acetate ( Wy8678 acetate )
产品货号. M13664 CAS No. 23256-50-0
一种 α2 肾上腺素受体，用作抗高血压化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥224 | 有现货 |
|
| 500MG | ￥376 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥260 | 有现货 |
|
生物学信息
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产品名称Guanabenz acetate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述一种 α2 肾上腺素受体，用作抗高血压化合物。
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产品描述An α2 adrenergic receptor that is used as an antihypertensive drug; has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex; also has antiparasitic activity against replicative stages of Toxoplasma.Hypertension Approved(In Vitro):Guanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).
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体外实验Guanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).
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体内实验——
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同义词Wy8678 acetate
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通路GPCR/G Protein
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靶点Adrenergic Receptor
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受体α2A-adrenergic receptor| α2B-adrenergic receptor| α2C-adrenergic receptor
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研究领域Cardiovascular Disease
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适应症Hypertension
化学信息
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CAS Number23256-50-0
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分子量291.1339
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分子式C10H12Cl2N4O2
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 51 mg/ml
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SMILESNC(N/N=C/C1=C(Cl)C=CC=C1Cl)=N.CC(O)=O
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化学全称Hydrazinecarboximidamide, 2-[(2,6-dichlorophenyl)methylene]-, acetate (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Das I, et al. Science. 2015 Apr 10;348(6231):239-42.
2. Crespillo-Casado A, et al. Elife. 2017 Apr 27;6. pii: e26109.
3. Benmerzouga I, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6939-45.
产品手册
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