• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Flopropione

CAS No. 2295-58-1

Flopropione ( —— )

产品货号. M13637 CAS No. 2295-58-1

Flopropione 是一种解痉剂或解痉剂,可作为 5-HT1A 受体拮抗剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥184 有现货
100MG ¥260 有现货
200MG ¥372 有现货
500MG ¥611 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥302 有现货

生物学信息

  • 产品名称
    Flopropione
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Flopropione 是一种解痉剂或解痉剂,可作为 5-HT1A 受体拮抗剂。
  • 产品描述
    Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist(In Vivo):The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.
  • 体外实验
    ——
  • 体内实验
    The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.
  • 同义词
    ——
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT1A
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    2295-58-1
  • 分子量
    182.18
  • 分子式
    C9H10O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 36 mg/mL (197.61 mM); DMSO: 36 mg/mL (197.61 mM)
  • SMILES
    CCC(=O)C1=C(O)C=C(O)C=C1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Aso Y, et al. J Pharm Sci, 2000, 89(3), 408-416.
产品手册
关联产品
  • Pimavanserin

    Pimavanserin(ACP-103) 是一种有效的选择性 5-HT2A 受体反向激动剂,在基于细胞的功能测定中,平均 pIC50 为 8.7。

  • Lofepramine

    洛非帕明是一种有效的三环类抗抑郁药,广泛代谢为地昔帕明。

  • Hyperforin

    Hyperforin 是瞬时受体典型 6 (TRPC6) 通道激活剂。Hyperforin 通过激活 Ca2+ 传导非选择性典型 TRPC6 通道来调节 Ca2+ 水平。Hyperforin 还表现出多种药理活性,包括抗抑郁、抗肿瘤、抗痴呆、抗糖尿病等。Hyperforin 调节 γδ T 细胞分泌 IL-17α,改善Imiquimod 诱导的银屑病样小鼠皮肤炎症。