Sodium Aescinate ( —— )

产品货号. M13308 CAS No. 20977-05-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Sodium Aescinate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Sodium aescinate 是一种来源 Aesculus hippocastanum 种子的三萜皂苷，具有抗炎、抗氧化活性。Sodium aescinate 能通过靶向 CARMA3/NF-κB 途径，抑制抑制肝癌生长。
产品描述

Extracted from Aesculus wilsonii;Store the product in sealed,cool and dry condition.(In Vitro):Sodium aescinate can block signals transiting to downstream molecules AKT, ERK, inhibit the proliferation of breast cancer cell MCF-7 cell apoptosis and induced cell apoptosis by suppressing the activation of SRC.(In Vivo):Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities.Sodium aescinate treatment can alleviate the symptom of polycystic ovary syndrome (PCOS) in rat model through regulating the PI3K/Akt/GSK3-β pathway.
体外实验

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体内实验

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同义词

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通路

Angiogenesis
靶点

HIF/HIF Prolyl-hydroxylase
受体

HIF-1α
研究领域

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适应症

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CAS Number

20977-05-3
分子量

1123.21
分子式

C54H83NaO23
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM
SMILES

CC(C(C)OC(=O)C)C(=O)OCC12[C@H]3C[C@@]4(C(=CCC5C4(CCC6C5(CCC([C@]6(C)CO)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O[C@@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O)O)O)C)C)C1CC([C@@H](C2O)O3)(C)C)C.[Na+]
化学全称

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