DDX3-IN-16d ( —— )

产品货号. M13009 CAS No. 1919828-83-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

DDX3-IN-16d
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

DEAD-box 多肽 3 (DDX3) 的小分子抑制剂 (IC50=0.3 uM)。
产品描述

A small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses; shows a broad spectrum of antiviral activity with EC50 of 0.97-16.5 uM (HIV, HCV, DENV, and WNV), retaines full activity against HIV drug-resistant strains (EC50<1 uM); exhibts a good safety profile and bioavailability in rats.
体外实验

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体内实验

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同义词

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通路

Microbiology/Virology
靶点

HIV
受体

HIV
研究领域

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适应症

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1. Brai A, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93.

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