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Sulfapyridine

CAS No. 144-83-2

Sulfapyridine ( A 499 | A499 | A-499 | Sulfapyridine | Plurazol | Pyriamid )

产品货号. M11918 CAS No. 144-83-2

Sulfapyridine(Dagenan) 是一种磺酰胺类抗菌剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥300 有现货
1G ¥376 有现货
1 mL x 10 mM in DMSO ¥437 有现货

生物学信息

  • 产品名称
    Sulfapyridine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Sulfapyridine(Dagenan) 是一种磺酰胺类抗菌剂。
  • 产品描述
    Sulfapyridine(Dagenan) is a sulfonamide antibacterial.(In Vitro):ulfapyridine inhibits production of IL-8, chemokine (C-X-C motif) ligand 1 (CXCL1), and monocyte chemotactic protein-1 (MCP-1) in synovial cells of rheumatoid arthritis (RA).MIC range of Sulfapyridine for Y. enterocolitica is 3.1-25 μg/mL and for Salmonella 25-100 μg/mL. Campylobacter jejuni/coli are less susceptible to Sulfapyridine with MIC values ranging from 200 to 800 μg/mL. Shigella and three of five E. coli strains are resistant to 1600 μg/mL of sulfapyridine. Two strains of E. coli are inhibited by 25 μg/mL.(In Vivo):Sulfapyridine (1 and 10 μg/kg; i.p.) significantly inhibits systemic allergic reaction induced by compound 48/80 in rats.
  • 体外实验
    Sulfapyridine inhibits production of IL-8, chemokine (C-X-C motif) ligand 1 (CXCL1), and monocyte chemotactic protein-1 (MCP-1) in synovial cells of rheumatoid arthritis (RA).MIC range of Sulfapyridine for Y. enterocolitica is 3.1-25 μg/mL and for Salmonella 25-100 μg/mL. Campylobacter jejuni/coli are less susceptible to Sulfapyridine with MIC values ranging from 200 to 800 μg/mL. Shigella and three of five E. coli strains are resistant to 1600 μg/mL of sulfapyridine. Two strains of E. coli are inhibited by 25 μg/mL.
  • 体内实验
    Sulfapyridine (1 and 10 μg/kg; i.p.) significantly inhibits systemic allergic reaction induced by compound 48/80 in rats.
  • 同义词
    A 499 | A499 | A-499 | Sulfapyridine | Plurazol | Pyriamid
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    DHPS
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    144-83-2
  • 分子量
    249.29
  • 分子式
    C11H11N3O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 1 mg/mL (4.01 mM)
  • SMILES
    O=S(NC1=NC=CC=C1)(C2=CC=C(N)C=C2)=O
  • 化学全称
    4-amino-N-(pyridin-2-yl)benzenesulfonamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.McDonald M, et al. J Chromatogr A. 2009 Nov 13;1216(46):8110-6.
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