CTx0294885 ( CTX0294885 | CTX 0294885 | CTX-0294885 )

产品货号. M11865 CAS No. 1439934-41-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

CTx0294885
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

CTX-0294885是一种新型双苯氨基嘧啶；在体外对多种激酶表现出抑制活性。
产品描述

CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro, and further developed it into a Sepharose-supported kinase capture reagent.(In Vitro):CTX-0294885 is a kinase capture tool in large-scale kinome profiling experiments, with 185 kinases identified as total protein, and 179 identified from TiO2 enrichment for phosphopeptides in MDA-MB-231 cells (by quantitative MS).CTX-0294885 captures all members of the AKT family that is not identified from previous studies using other kinase capture reagents.
体外实验

CTX-0294885 is a kinase capture tool in large-scale kinome profiling experiments, with 185 kinases identified as total protein, and 179 identified from TiO2 enrichment for phosphopeptides in MDA-MB-231 cells (by quantitative MS).CTX-0294885 captures all members of the AKT family that is not identified from previous studies using other kinase capture reagents.
体内实验

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同义词

CTX0294885 | CTX 0294885 | CTX-0294885
通路

Others
靶点

Other Targets
受体

Kinase capture reagent
研究领域

Other Indications
适应症

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CAS Number

1439934-41-4
分子量

437.93
分子式

C22H24ClN7O
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM
SMILES

O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCNCC4)C=C3)=NC=C2Cl
化学全称

2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide

1. Zhang L, et al. J Proteome Res. 2013 Jul 5;12(7):3104-16.

计算器

产品手册

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