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Tetracaine hydrochloride

CAS No. 136-47-0

Tetracaine hydrochloride ( —— )

产品货号. M11504 CAS No. 136-47-0

盐酸丁卡因 (Pontocaine) 是丁卡因的盐酸盐形式,是一种有效的局部麻醉剂和通道功能变构抑制剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥148 有现货
1G ¥224 有现货

生物学信息

  • 产品名称
    Tetracaine hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    盐酸丁卡因 (Pontocaine) 是丁卡因的盐酸盐形式,是一种有效的局部麻醉剂和通道功能变构抑制剂。
  • 产品描述
    Tetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. Tetracaine hydrochloride (Pontocaine) is used to block temporarily the pain "message" that is sent along the nerves that connect the eyes to the brain. Tetracaine hydrochloride (Pontocaine) is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. (In Vitro):Tetracaine hydrochloride (Amethocaine hydrochloride) is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine hydrochloride is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
  • 体外实验
    Tetracaine hydrochloride (Amethocaine hydrochloride) is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine hydrochloride is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Membrane Transporter/Ion Channel
  • 靶点
    Sodium Channel
  • 受体
    Sodium Channel
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    136-47-0
  • 分子量
    300.83
  • 分子式
    C15H24N2O2·HCl
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 30 mg/mL (99.72 mM); Water: 60 mg/mL (199.45 mM); DMSO: 60 mg/mL (199.45 mM)
  • SMILES
    Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Leng T, et al. Mol Pain. 2013 Jun 10;9:27
产品手册
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