Duloxetine hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

盐酸度洛西汀是一种选择性血清素和去甲肾上腺素再摄取抑制剂。

Duloxetine hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor .(In Vitro):Duloxetine ((S)-Duloxetine hydrochloride) (sold under the brand names Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela, Dulane) is a serotonin-norepinephrine reuptake inhibitor(SNRI) manufactured and marketed by Eli Lilly. It is prescribed for major depressive disorder and generalized anxiety disorder (GAD). Duloxetine also has approval for use in osteoarthiritis and musculoskeletal pain. Duloxetine failed the US approval for stress urinary incontinence amidst concerns over liver toxicity and suicidal events; however, it was approved for this indication in Europe, where it is recommended as an add-on medication in stress urinary incontinence instead of surgery. It can also relieve the symptoms of painful peripheral neuropathy, particularly diabetic neuropathy, and it is used to control the symptoms of fibromyalgia. The main uses of duloxetine are in major depressive disorder, general anxiety disorder, stress urinary incontinence, painful peripheral neuropathy,fibromyalgia, and chronic musculoskeletal pain associated with osteoarthritis and chronic lower back pain. It is being studied for various other indications.

Duloxetine ((S)-Duloxetine hydrochloride) (sold under the brand names Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela, Dulane) is a serotonin-norepinephrine reuptake inhibitor(SNRI) manufactured and marketed by Eli Lilly. It is prescribed for major depressive disorder and generalized anxiety disorder (GAD). Duloxetine also has approval for use in osteoarthiritis and musculoskeletal pain. Duloxetine failed the US approval for stress urinary incontinence amidst concerns over liver toxicity and suicidal events; however, it was approved for this indication in Europe, where it is recommended as an add-on medication in stress urinary incontinence instead of surgery. It can also relieve the symptoms of painful peripheral neuropathy, particularly diabetic neuropathy, and it is used to control the symptoms of fibromyalgia. The main uses of duloxetine are in major depressive disorder, general anxiety disorder, stress urinary incontinence, painful peripheral neuropathy,fibromyalgia, and chronic musculoskeletal pain associated with osteoarthritis and chronic lower back pain. It is being studied for various other indications.

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LY248686

Endocrinology/Hormones

5-HT Receptor

Sert (Sodium-dependent)| DA transporter| Noradrenaline transporter (Sodium-dependent)

Neurological Disease

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136434-34-9

333.88

C18H20ClNOS

>98% (HPLC)

DMSO: 67 mg/mL (200.67 mM)

CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32

(3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine

(-20℃)

With Ice Pack

≥ 2 years