Methylcobalamin
CAS No. 13422-55-4
Methylcobalamin ( Algobaz, Cobaday, Cobalt-methylcobalamin, Cobamet, Cobametin )
产品货号. M11370 CAS No. 13422-55-4
甲钴胺是一种钴胺素,是维生素 B12 的一种形式。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ¥138 | 有现货 |
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| 100MG | ¥335 | 有现货 |
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| 200MG | ¥527 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Methylcobalamin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述甲钴胺是一种钴胺素,是维生素 B12 的一种形式。
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产品描述Methylcobalamin a cobalamin, is a form of vitamin B12.(In Vitro):Methylcobalamin (CH3-B12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyanide is replaced by a methyl group. Methylcobalamin (CH3-B12) features an octahedral cobalt(III) centre. Methylcobalamin (CH3-B12) can be obtained as bright red crystals. From the perspective of coordination chemistry, Methylcobalamin (CH3-B12) is notable as a rare example of a compound that contains metal-alkyl bonds. Methylcobalamin (CH3-B12) is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia. Methylcobalamin (CH3-B12) is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis. From Wikipedia.
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体外实验——
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体内实验——
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同义词Algobaz, Cobaday, Cobalt-methylcobalamin, Cobamet, Cobametin
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通路Others
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靶点Other Targets
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受体Others
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研究领域Metabolic Disease
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适应症——
化学信息
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CAS Number13422-55-4
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分子量1344.38
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分子式C63H91CoN13O14P
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纯度>98% (HPLC)
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溶解度Water: 10mM
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SMILES[CH3-].[Co+3].C[C@@H](CNC(=O)CC[C@]1(C)[C@@H](CC(=O)N)[C@H]2[N-]/C/1=C(/C)\C3=N\C(=C/C4=N\C(=C(\C)/C5=N[C@]2(C)[C@@](C)(CC(=O)N)[C@@H]5CCC(=O)N)\[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)\C(C)(C)[C@@H]3CCC(=O)N)OP(=O)([O-])O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
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化学全称Cobinamide, cobalt-methyl derivative, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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4-Acetamidobenzenesu...
4-乙酰氨基苯磺酰叠氮化物是一种化合物。
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Neuromedin (U25), hu...
Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds.
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OD1
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.
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