Fudosteine ( SS320A )

产品货号. M11291 CAS No. 13189-98-5

COA

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HPLC

MSDS

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产品名称

Fudosteine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fudosteine 是一种新型粘液活性剂和 MUC5AC 粘蛋白高分泌抑制剂。
产品描述

Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor. (In Vitro):Fudosteine (50, 100, 200 mg/kg) decreases the LPS-induced p-ERK1/2 and p-p38 MAPK levels in the rat lungs. The TNF-α-induced increase in MUC5AC mRNA expression is inhibited by pretreatment with 1 mM Fudosteine.
体外实验

Fudosteine (50, 100, 200 mg/kg) decreases the LPS-induced p-ERK1/2 and p-p38 MAPK levels in the rat lungs. The TNF-α-induced increase in MUC5AC mRNA expression is inhibited by pretreatment with 1 mM Fudosteine.
体内实验

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同义词

SS320A
通路

Others
靶点

Other Targets
受体

MUC5AC mucin
研究领域

Metabolic Disease
适应症

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1.Rhee CK, et al. Eur Respir J. 2008 Nov;32(5):1195-202.

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