GS967 ( GS967 | GS-967 | GS 967 | GS458967 )

产品货号. M11095 CAS No. 1262618-39-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

GS967
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

GS967 是一种新型、有效、选择性的心脏晚钠电流 (late INa) 抑制剂。
产品描述

GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa); inhibits ATX-II-induced late I(Na) in ventricular myocytes and isolated hearts with IC(50) values of 0.13 and 0.21 μM, respectively.
体外实验

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体内实验

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同义词

GS967 | GS-967 | GS 967 | GS458967
通路

Membrane Transporter/Ion Channel
靶点

Sodium Channel
受体

late?INa?,isolated hearts| late?INa?,ventricular myocytes
研究领域

Cardiovascular Disease
适应症

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CAS Number

1262618-39-2
分子量

347.22
分子式

C14H7F6N3O
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM
SMILES

FC(C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21)(F)F
化学全称

6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)(1,2,4)triazolo(4,3-a)pyridine

1.Belardinelli L, et al. J Pharmacol Exp Ther. 2013 Jan;344(1):23-32.

计算器

产品手册

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