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Efonidipine hydrochloride monoethanolate
CAS No. 111011-76-8
Efonidipine hydrochloride monoethanolate ( NZ-105 hydrochloride monoethanolate )
产品货号. M10410 CAS No. 111011-76-8
Efonidipine (NZ-105) 是一种有效的 T 型和 L 型双重钙通道阻滞剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥391 | 有现货 |
|
| 10MG | ￥629 | 有现货 |
|
| 25MG | ￥1172 | 有现货 |
|
| 50MG | ￥2213 | 有现货 |
|
| 100MG | ￥2952 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥692 | 有现货 |
|
生物学信息
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产品名称Efonidipine hydrochloride monoethanolate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Efonidipine (NZ-105) 是一种有效的 T 型和 L 型双重钙通道阻滞剂。
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产品描述Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
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体外实验——
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体内实验——
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同义词NZ-105 hydrochloride monoethanolate
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通路GPCR/G Protein
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靶点Calcium Channel
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受体Calcium Channel
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研究领域Cardiovascular Disease
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适应症——
化学信息
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CAS Number111011-76-8
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分子量714.1846
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分子式C36H45ClN3O8P
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纯度>98% (HPLC)
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溶解度DMSO: 8.5 mg/mL
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SMILESCCO.CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl
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化学全称3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, hydrochloride, compd. with 2-[phenyl(phenylmethyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr;343(4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov;25(7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov;57(3):337-48.
产品手册
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