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Teriflunomide
CAS No. 108605-62-5
Teriflunomide ( A77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio. )
产品货号. M10335 CAS No. 108605-62-5
特立氟胺是来氟米特的活性代谢物，通过抑制嘧啶合成而发挥免疫调节剂的作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥103 | 有现货 |
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| 25MG | ￥198 | 有现货 |
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| 50MG | ￥305 | 有现货 |
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| 100MG | ￥446 | 有现货 |
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| 200MG | ￥651 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥111 | 有现货 |
|
生物学信息
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产品名称Teriflunomide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述特立氟胺是来氟米特的活性代谢物，通过抑制嘧啶合成而发挥免疫调节剂的作用。
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产品描述Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.
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体外实验——
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体内实验——
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同义词A77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio.
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体Dihydroorotate Dehydrogenase
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number108605-62-5
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分子量270.21
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分子式C12H9F3N2O2
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纯度>98% (HPLC)
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溶解度Ethanol: 1 mg/mL ,1; Water: <1 mg/mL (<1 mM); DMSO: 32 mg/mL (118.42 mM)
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SMILESC/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
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化学全称(Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide.
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Palmer AM. Curr Opin Investig Drugs. 2010 Nov;11(11):1313-23.
