Teriflunomide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

特立氟胺是来氟米特的活性代谢物，通过抑制嘧啶合成而发挥免疫调节剂的作用。

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.

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A77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio.

Metabolic Enzyme/Protease

Dehydrogenase

Dihydroorotate Dehydrogenase

Inflammation/Immunology

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108605-62-5

270.21

C12H9F3N2O2

>98% (HPLC)

Ethanol: 1 mg/mL ,1; Water: <1 mg/mL (<1 mM); DMSO: 32 mg/mL (118.42 mM)

C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O

(Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide.

(-20℃)

With Ice Pack

≥ 2 years