AUTEN-99 hydrobromide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

一种小分子自噬增强剂，可抑制肌管蛋白相关磷酸酶 MTMR14/Jumpy。

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy; induces autophagic flux and promotes cell survival in mammalian cell cultures; increases the number of autophagic structures in mice and Drosophila, and effectively penetrates through a blood-brain barrier model; impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson's and Huntington's diseases.

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AUTEN99 hydrobromide

Autophagy

Autophagy

Autophagy

Neurological Disease

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1049780-58-6

359.285

C17H15BrN2S

>98% (HPLC)

In Vitro:?DMSO : ≥ 7.5 mg/mL (20.88 mM)

C1CN2C=C(SC2=N1)C3=CC=C(C=C3)C4=CC=CC=C4.Br

2-([1,1'-biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide

(-20℃)

With Ice Pack

≥ 2 years