Trospium chloride ( Relaspium )

产品货号. M10206 CAS No. 10405-02-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Trospium chloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Trospium chloride 是具有口服活性的，特异性、竞争性的毒蕈碱胆碱能受体 (mAChRs) 拮抗剂，具有抗毒蕈碱活性。Trospium chloride 能以高亲和力结合毒蕈碱受体 M1、M2 和 M3，但不与烟碱、胆碱能受体结合。
产品描述

Trospium is a urinary antispasmodic. It is sold under the brand name Sanctura in the US, and as Trosec in Canada.
体外实验

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体内实验

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同义词

Relaspium
通路

Endocrinology/Hormones
靶点

AChR
受体

mAChR
研究领域

Neurological Disease
适应症

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CAS Number

10405-02-4
分子量

427.97
分子式

C25H30ClNO3
纯度

>98% (HPLC)
溶解度

Ethanol: 42 mg/mL (98.14 mM); Water: 86 mg/mL (200.95 mM); DMSO: 41 mg/mL (95.8 mM)
SMILES

O=C(C(C1=CC=CC=C1)(O)C2=CC=CC=C2)O[C@@H]3C[C@H]([N+]45CCCC4)CC[C@H]5C3.[Cl-]
化学全称

(1R,3s,5S)-3-(2-hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride

1.Karaman A, et al. Urology. 2013 Jul;82(1):194-200.

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