ML-346 ( ML346 )

产品货号. M10056 CAS No. 100872-83-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ML-346
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

一种新型 HSP70 激活剂，EC50 为 4.6 uM。
产品描述

A novel activator of HSP70 with EC50 of 4.6 uM; induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models, which are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2.
体外实验

——
体内实验

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同义词

ML346
通路

Cytoskeleton/Cell Adhesion Molecules
靶点

HSP
受体

HSP70
研究领域

Cancer
适应症

——

CAS Number

100872-83-1
分子量

272.2561
分子式

C14H12N2O4
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 29 mg/mL
SMILES

O=C(NC(NC/1=O)=O)C1=C\C=C\C2=CC=C(OC)C=C2
化学全称

2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[3-(4-methoxyphenyl)-2-propen-1-ylidene]-

1. Calamini B, et al. Probe Reports from the NIH Molecular Libraries Program.

计算器

产品手册

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