Letolizumab
CAS No. 1450981-87-9
Letolizumab ( —— )
产品货号. M36807 CAS No. 1450981-87-9
Letolizumab (BMS-986004) 是一种靶向 CD40L 的单克隆抗体,其产生是为了表达缺乏效应器功能的突变 IgG1,包括 Fc 结合和补体固定。Letolizumab 降低了排斥反应、血栓栓塞,延长了存活时间。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥2183 | 有现货 |
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| 5MG | ¥3618 | 有现货 |
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| 10MG | ¥5774 | 有现货 |
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| 25MG | ¥8446 | 有现货 |
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| 50MG | ¥11417 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Letolizumab
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Letolizumab (BMS-986004) 是一种靶向 CD40L 的单克隆抗体,其产生是为了表达缺乏效应器功能的突变 IgG1,包括 Fc 结合和补体固定。Letolizumab 降低了排斥反应、血栓栓塞,延长了存活时间。
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产品描述Letolizumab (BMS-986004) is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time.
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体外实验——
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体内实验Animal Model:Rhesus macaques after renal transplantation.Dosage:2, 10 and 20 mg/kg.Administration:Intravenous injection; once a week for 10 weeks.Result:Increased the survival time.
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同义词——
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通路Others
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靶点Other Targets
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受体Immunology/Inflammation related
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研究领域——
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适应症——
化学信息
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CAS Number1450981-87-9
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Karnell JL, et al. Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond. Adv Drug Deliv Rev. 2019 Feb 15;141:92-103. ?
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