Letaplimab
CAS No. 2283356-07-8
Letaplimab ( —— )
产品货号. M37171 CAS No. 2283356-07-8
Letaplimab (IBI-188) 一种人源化 IgG4 单克隆抗 CD47 抗体。CD47 在癌细胞中过表达,是 SIRPα 的配体。Letaplimab 增强肿瘤细胞吞噬作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥3191 | 有现货 |
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| 5MG | ¥5208 | 有现货 |
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| 10MG | ¥7970 | 有现货 |
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| 25MG | ¥11965 | 有现货 |
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| 50MG | ¥15484 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Letaplimab
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Letaplimab (IBI-188) 一种人源化 IgG4 单克隆抗 CD47 抗体。CD47 在癌细胞中过表达,是 SIRPα 的配体。Letaplimab 增强肿瘤细胞吞噬作用。
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产品描述Letaplimab (IBI-188) is a humanized IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number2283356-07-8
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Miao Miao, et al. A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome. MYELODYSPLASTIC SYNDROMES-CLINICAL AND EPIDEMIOLOGICAL NOVEMBER 15, 2022.
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