Lasiocarpine ( —— )

产品货号. M31055 CAS No. 303-34-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Lasiocarpine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Lasiocarpine is a pyrrolizidine alkaloid, it has acute cytotoxicity in human and hepatic cell lines.
产品描述

Lasiocarpine is a pyrrolizidine alkaloid, it has acute cytotoxicity in human and hepatic cell lines.
体外实验

Lasiocarpine is toxic only after its metabolic conversion to the toxic intermediate, known as dehydrolasiocarpine.Dehydrolasiocarpine and other putative didehydropyrrolizidine alkaloids (the pyrrolic esters) are very reactive,they attack nucleophilic macromolecules such as DNA and proteins, eliciting severe toxicities, including liver veno-occlusive disease and tumors.Lasiocarpine is mainly metabolized in vitro through five metabolic pathways, dehydrogenation, ester bond cleavage, demethylation.
体内实验

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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