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KISS1-305
CAS No. 872717-97-0
KISS1-305 ( —— )
产品货号. M30166 CAS No. 872717-97-0
KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation.KISS1-305 is a proto- type peptide that resists plasma protease degradation but has suboptimal KISS1R agonistic activity in vitro.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称KISS1-305
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation.KISS1-305 is a proto- type peptide that resists plasma protease degradation but has suboptimal KISS1R agonistic activity in vitro.
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产品描述KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation.KISS1-305 is a proto- type peptide that resists plasma protease degradation but has suboptimal KISS1R agonistic activity in vitro.(In Vivo):KISS1-305 (4 nmol/h; s.c.) shows suppression of pituitary-gonadal functions. KISS1-305 causes substantial elevations of plasma LH and testosterone, followed by abrupt reductions of both hormone levels.?KISS1-305 also reduced genital organ weight more profoundly than leuprolide. In mechanistic studies, chronic KISS1-305 administration only transiently induced c-Fos expression in GnRH neurons, suggesting that GnRH-neural response was attenuated over time.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number872717-97-0
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分子量1165.3
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分子式C56H76N16O12
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Matsui H, et al.Chronic?administration?of the?metastin/kisspeptin?analog?KISS1-305?or the?investigational?agent?TAK-448?suppresses?hypothalamic?pituitary?gonadal?function?and?depletes?plasma?testosterone?in?adult?male?rats.Endocrinology.?2012 Nov;153(11):5297-308.
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