Isorubrofusarin-6-O-β-gentiobioside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Isorubrofusarin-6-O-β-gentiobioside 源自 Cassia obtusifolia Linn 种子，对 AChE 和 BACE1 表现出良好的抑制活性。

Isorubrofusarin-6-O-β-gentiobioside is derived from from Cassia obtusifolia Linn seeds and shows promising inhibitory activity against AChE and BACE1.(In Vitro):The SARs results emphasized the importance of gentiobiosyl moiety in Isorubrofusarin-6-O-β-gentiobioside for AChE inhibition, whereas the presence of hydroxyl group at C-8 and the glucosyl moiety at the C-6 position in the Isorubrofusarin-6-O-β-gentiobioside appeared to largely determine BACE1 inhibition.

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Isorubrofusarin 10-gentiobioside

Metabolic Enzyme/Protease

BACE

BACE

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200127-93-1

596.538

C27H32O15

>98% (HPLC)

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COc1cc(O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)c2c(c1)cc(O)c1c2oc(C)cc1=O

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(-20℃)

With Ice Pack

≥ 2 years