ISX-1
CAS No. 909207-35-8
ISX-1 ( —— )
产品货号. M33990 CAS No. 909207-35-8
ISX-1 是一种异恶唑。 ISX-1 具有抗脂肪生成和促成骨活性。 ISX-1 可用于骨量减少和骨质疏松症的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥1227 | 有现货 |
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| 5MG | ¥1760 | 有现货 |
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| 10MG | ¥2487 | 有现货 |
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| 25MG | ¥3722 | 有现货 |
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| 50MG | ¥5302 | 有现货 |
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| 100MG | ¥7160 | 有现货 |
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| 200MG | ¥9639 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ISX-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述ISX-1 是一种异恶唑。 ISX-1 具有抗脂肪生成和促成骨活性。 ISX-1 可用于骨量减少和骨质疏松症的研究。
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产品描述ISX-1 is an isoxazole. ISX-1 has anti-adipogenic and pro-osteogenic activities. ISX-1 can be used for the research of osteopenia and osteoporosis.
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体外实验RT-PCRCell Line:Human bone marrow mesenchymal stem cells (hBMSCs)Concentration:0, 1.3, 6.5 and 33 μM Incubation Time:3 days Result:Inhibited the mRNA induction of PPARγ and FABP4 genes under the adipogenic differentiation of hBMSCs and showed no effect on C/EBPα expression.Western Blot Analysis Cell Line:HEK 293 cells Concentration:6.5 and 33 μM Incubation Time:6.5 and 33 μM Result:Increased both the amount of activated and total β-catenin.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number909207-35-8
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分子量302.35
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分子式C14H14N4O2S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 50 mg/mL (165.37 mM; 超声助溶 )
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SMILESC(NCCCN1C=CN=C1)(=O)C=2C=C(ON2)C3=CC=CS3
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Nawa, Katsuhiko et al. Discovering small molecules that inhibit adipogenesis and promote osteoblastogenesis: unique screening and Oncostatin M-like activity. Differentiation. 2013 Jul-Sep;86(1-2):65-74. ?
产品手册
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