021-51111890
购物车（0）
sales@molnova.cn
I-152
CAS No. 311343-11-0
I-152 ( —— )
产品货号. M36625 CAS No. 311343-11-0
I-152 是一种含有 N-乙酰半胱氨酸 (NAC) 和半胱胺 (MEA) 的共轭物。I-152 激活 NRF2 和 ATF4 信号。I-152 具有抗增殖活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1008 | 有现货 |
|
| 5MG | ￥1696 | 有现货 |
|
| 10MG | ￥2907 | 有现货 |
|
| 25MG | ￥4841 | 有现货 |
|
| 50MG | ￥7765 | 有现货 |
|
| 100MG | ￥12164 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称I-152
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述I-152 是一种含有 N-乙酰半胱氨酸 (NAC) 和半胱胺 (MEA) 的共轭物。I-152 激活 NRF2 和 ATF4 信号。I-152 具有抗增殖活性。
-
产品描述I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties.
-
体外实验Western Blot Analysis Cell Line:RAW 264.7 cells.Concentration:0.062, 0.125, 0.25, 1, 5 or 10 mM.Incubation Time:2 h or 24 h.Result:Reduced the expression of NRF2/β-ACTIN, increased the expression of GCLM.
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number311343-11-0
-
分子量264.36
-
分子式C9H16N2O3S2
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (378.27 mM; 超声助溶 )
-
SMILES[C@H](C(NCCSC(C)=O)=O)(NC(C)=O)CS
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Crinelli R, et al. Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. Antioxidants (Basel). 2021 Jan 26;10(2):175. ?
产品手册
关联产品
-
Larixyl acetate
乙酸落叶松酯是一种生物活性化学品。
-
Egg Laying Hormone, ...
Egg-laying hormone (ELH) is a neuropeptide synthesized by the bag cell neurons, Egg-laying hormone (ELH) induces egg laying and its correlated behavior in Aplysia californica. Egg-laying hormone (ELH) has been purified to homogeneity and Egg-laying hormone (ELH)'s primary structure has been determined. Egg-laying hormone (ELH) have 36 amino acid residues with a Mr of 4385 and a calculated isoelectric point of 9.7. Egg Laying Hormone of Aplysia induces a voltage-dependent slow inward current carried by Na+ in an identified motoneuron.
-
Praeruptorin C
Praeruptorin C 是白花前胡 (Peucedanum praeruptorum) 的一种主要生物活性成分。Praeruptorin C 是一种钙 (calcium) 拮抗剂，pD2′ 值为 5.7。
