Gamma-Methylleucine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

γ-甲基亮氨酸是铜催化不对称迈克尔反应的助剂。

Gamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.(In Vivo):gamma-Methylleucine improved the binding affinity of the peptide for Y2R but also increased its anorectic activity in lean mice . Gamma-methylleucine resulted in loss of or significantly decreased the biological activity of ET-1, while high affinity for the ETA (IC50 = 0.42-0.70 nM) and ETB (IC50 = 0.17-0.43 nM) receptor was retained . Gamma-methylleucine was shown to have high antagonist activitiesin Sarafotoxin S6c-induced vasoconstriction of rabbit pulmonary artery (ET-1: pA2 8.4) and have the desirable characteristic of possessing no agonist activity at either receptor subtype .

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances.

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gamma-Methyl-L-leucine | L-Neopentylglycine | 2-Amino-3-tert-butylpropionic acid

Others

Other Targets

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57224-50-7

145.202

C7H15NO2

>98% (HPLC)

In Vitro:?H2O : 25 mg/mL (172.18 mM)

CC(C)(C)C[C@H](N)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years