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Furafylline
CAS No. 80288-49-9
Furafylline ( —— )
产品货号. M20761 CAS No. 80288-49-9
Furafylline 是人细胞色素 P450 (CYP)1A2 的选择性抑制剂 (IC50 : 0.07 μM)，
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2406 | 有现货 |
|
| 10MG | ￥3750 | 有现货 |
|
| 25MG | ￥6205 | 有现货 |
|
| 50MG | ￥8667 | 有现货 |
|
| 100MG | ￥11745 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Furafylline
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Furafylline 是人细胞色素 P450 (CYP)1A2 的选择性抑制剂 (IC50 : 0.07 μM)，
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产品描述Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM)
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体外实验——
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体内实验Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC50 of 0.07 μM in kinase experiment. Furafylline is a methylxanthine derivative that is introduced as a long-acting replacement for theophylline in the treatment of asthma. Administration of Furafylline is associated with an elevation in plasma levels of caffeine, due to inhibition of caffeine oxidation, a reaction catalysed by one or more hydrocarbon-inducible isoenzymes of P450. Furafylline has either very little or no effect on human monooxygenase activities catalysed by other isoenzymes of P450, including P4501ID1, P4501IC, P450IIIA.
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同义词——
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通路Metabolic Enzyme/Protease
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靶点P450
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受体CYP450
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研究领域——
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适应症——
化学信息
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CAS Number80288-49-9
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分子量260.25
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分子式C12H12N4O3
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纯度>98% (HPLC)
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溶解度DMSO:12.5 mg/mL (48.03 mM)
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SMILESCc1nc2n(Cc3ccco3)c(=O)n(C)c(=O)c2[nH]1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Sesardic D Boobis A R Murray B P et al. Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.[J]. British Journal of Clinical Pharmacology 1990 29(6):651-663.
产品手册
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