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Epithalon

CAS No. 307297-39-8

Epithalon ( —— )

产品货号. M30155 CAS No. 307297-39-8

Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1130 有现货
10MG ¥2074 有现货
25MG ¥4471 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    Epithalon
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.
  • 产品描述
    Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.(In Vitro):Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.(In Vivo):Epitalon increases the lifespan of mice and fruit flies and restores the circadian rhythms of melatonin and cortisol production in old rhesus monkeys. At the same time, Epitalon prolongs the functional integrity of the eye retina in Campbell rats with hereditary Retinitis Pigmentosa and improves the visual functions in patients with pigmental retinal degeneration.
  • 体外实验
    Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.
  • 体内实验
    Epitalon increases the lifespan of mice and fruit flies and restores the circadian rhythms of melatonin and cortisol production in old rhesus monkeys. At the same time, Epitalon prolongs the functional integrity of the eye retina in Campbell rats with hereditary Retinitis Pigmentosa and improves the visual functions in patients with pigmental retinal degeneration.
  • 同义词
    ——
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    Telomerase
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    307297-39-8
  • 分子量
    390.35
  • 分子式
    C14H22N4O9
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?H2O : ≥ 50 mg/mL (128.09 mM)*)
  • SMILES
    ——
  • 化学全称
    Sequence:{Ala}{Glu}{Asp}{Gly}

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Khavinson VKh. et al. Peptides and Ageing. Neuro Endocrinol Lett. 2002;23 Suppl 3:11-144.
产品手册
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