Diethyl-pythiDC

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Diethy-pythiDC 是一种胶原蛋白脯氨酰 4-羟化酶抑制剂。

Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor. (In Vitro):In MDA-MB-231 cells, Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. None of the esterified Diethyl-pythiDC exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC appear to be normal at concentrations as high as 500 μM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin.

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Others

Other Targets

Endogenous Metabolite

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1821370-70-0

306.34

C14H14N2O4S

>98% (HPLC)

In Vitro:?DMSO : 33.33 mg/mL (108.80 mM)

CCOC(=O)c1cnc(s1)-c1ccc(cn1)C(=O)OCC

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(-20℃)

With Ice Pack

≥ 2 years