DS-6930b ( DS-6930 calcium salt | DS6930b )

产品货号. M16962 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

DS-6930b
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

DS-6930b（DS-6930 钙盐）是 DS-6930 的钙盐，DS-6930 是一种新型强效选择性 PPARγ 激动剂，EC50 为 41 nM。
产品描述

DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity.Diabetes Discontinued.
体外实验

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体内实验

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同义词

DS-6930 calcium salt | DS6930b
通路

Metabolic Enzyme/Protease
靶点

PPAR
受体

PPAR
研究领域

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适应症

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CAS Number

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分子量

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分子式

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纯度

>98% (HPLC)
溶解度

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SMILES

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化学全称

3-((6-((3,5-dimethylpyridin-2-yl)oxy)-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)benzoic acid 1/2 calcium