Crizanlizumab ( —— )

产品货号. M36878 CAS No. 1690318-25-2

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产品名称

Crizanlizumab
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Crizanlizumab 是一种抗-P-选择素 (P-selectin) 单克隆抗体。Crizanlizumab 可与 P-选择素结合并阻断其与 P-选择素糖蛋白配体 1 (PSGL-1) 的相互作用。Crizanlizumab 可阻止血管阻塞性危象 (VOC)，可用于镰状细胞病的研究。
产品描述

Crizanlizumab is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs) and can be used for research of sickle cell disease.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

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适应症

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1. Hannah A. Blair, et al. Crizanlizumab: First Approval. Drugs. 80, 79-84 (2020).

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