Cinepazide
CAS No. 23887-46-9
Cinepazide ( —— )
产品货号. M13690 CAS No. 23887-46-9
一种脑血管扩张剂,具有钙阻滞剂的作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥7857 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Cinepazide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述一种脑血管扩张剂,具有钙阻滞剂的作用。
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产品描述A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.Ischemia Approved.
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体外实验——
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体内实验Cinepazide (intravenous?injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner and the effect is partially inhibited by Aminophylline (HY-B0140)?in dogs.
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同义词——
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Cardiovascular Disease
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适应症Ischemia
化学信息
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CAS Number23887-46-9
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分子量417.4986
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分子式C22H31N3O5
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCOC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCN(CC2)CC(=O)N3CCCC3
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化学全称Piperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (E)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Miwa S, et al. Jpn J Pharmacol. 1986 May;41(1):109-15.
2. Zhao J, et al. Neurol Sci. 2014 Jun;35(6):875-81.
3. Li Y, et al. Biol Pharm Bull. 2017 Mar 1;40(3):249-255.
产品手册
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