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CG347B
CAS No. 1598426-03-9
CG347B ( —— )
产品货号. M23696 CAS No. 1598426-03-9
CG347B 是 HDAC6 的选择性抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥599 | 有现货 |
|
| 5MG | ￥988 | 有现货 |
|
| 10MG | ￥1596 | 有现货 |
|
| 25MG | ￥2859 | 有现货 |
|
| 50MG | ￥4358 | 有现货 |
|
| 100MG | ￥6051 | 有现货 |
|
| 500MG | ￥12636 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CG347B
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CG347B 是 HDAC6 的选择性抑制剂。
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产品描述CG347B is a selective inhibitor of HDAC6.
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体外实验HtrA1 is identified as a Cisplatin (HY-17394, CDDP) resistance-related gene in NSCLC cells, while CG347B shows no effect on normalized mRNA expression or protein level of HtrA1 in NCI-H460 (CDDP-resistant) cells.CG347B (200 nM; 48 h) slightly rescues the Foxp3 expression inhibition induced by IL-4 (15 ng/mL), indicating a potential inhibition happens on histone deacetylation in naive CD4+ T cells from WT B6 mice cultured under Treg-polarizing conditions (for 1-3 d).
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体内实验——
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同义词——
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC6
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研究领域——
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适应症——
化学信息
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CAS Number1598426-03-9
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分子量283.33
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分子式C16H17N3O2
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纯度>98% (HPLC)
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溶解度DMSO:249 mg/mL?(878.83 mM;?Need ultrasonic)
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SMILESCCOC(c1cnc(NC2(CC2)c2ccccc2)nc1)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Christopher M. YATES. Metalloenzyme inhibitor compounds. WO2018165520A1.
