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Blebbistatin
CAS No. 674289-55-5
Blebbistatin ( (±)-Blebbistatin )
产品货号. M24685 CAS No. 674289-55-5
Blebbistatin 是一种选择性非肌肉肌球蛋白 II (NMII) 抑制剂。它促进角膜内皮细胞（CEC）的定向迁移并加速伤口愈合。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥356 | 有现货 |
|
| 5MG | ￥567 | 有现货 |
|
| 10MG | ￥1077 | 有现货 |
|
| 25MG | ￥1831 | 有现货 |
|
| 50MG | ￥3216 | 有现货 |
|
| 100MG | ￥4844 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Blebbistatin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Blebbistatin 是一种选择性非肌肉肌球蛋白 II (NMII) 抑制剂。它促进角膜内皮细胞（CEC）的定向迁移并加速伤口愈合。
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产品描述Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell junctional integrity and barrier function.
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体外实验——
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体内实验Animal Model:New Zealand white rabbits (16-20 weeks; 3-3.5 kg) Dosage:0.05 mL; 20 μM Administration:Intracameral injection; daily; for 6 days Result:Resulted in significant improvement of corneal clarity and corneal edema resolution, implying the restoration of an intact corneal endothelial monolayer.
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同义词(±)-Blebbistatin
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通路Endocrinology/Hormones
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靶点ATPase
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受体non-muscle myosin II ATPases
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研究领域——
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适应症——
化学信息
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CAS Number674289-55-5
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分子量292.33
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分子式C18H16N2O2
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纯度>98% (HPLC)
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溶解度DMSO : 23 mg/mL (78.67 mM; Need ultrasonic)
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SMILESCc(cc1)cc(C(C2(CC3)O)=O)c1N=C2N3c1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ho WT, et al. Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics. J Mol Med (Berl). 2019 Sep;97(9):1345-1357.
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