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Belinostat
CAS No. 414864-00-9
Belinostat ( PXD101 )
产品货号. M14420 CAS No. 414864-00-9
Belinostat 是一种新型异羟肟酸型组蛋白脱乙酰酶 (HDAC) 抑制剂，具有抗肿瘤活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥316 | 有现货 |
|
| 10MG | ￥502 | 有现货 |
|
| 25MG | ￥794 | 有现货 |
|
| 50MG | ￥1191 | 有现货 |
|
| 100MG | ￥1758 | 有现货 |
|
| 200MG | ￥2811 | 有现货 |
|
| 500MG | ￥4682 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Belinostat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Belinostat 是一种新型异羟肟酸型组蛋白脱乙酰酶 (HDAC) 抑制剂，具有抗肿瘤活性。
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产品描述Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
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体外实验——
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体内实验——
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同义词PXD101
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC
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研究领域Cancer
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适应症——
化学信息
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CAS Number414864-00-9
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分子量318.35
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分子式C15H14N2O4S
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纯度>98% (HPLC)
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溶解度DMSO: 64 mg/mL (201.03 mM)
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SMILESC1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
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化学全称2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Savickiene J, et al. anticancer Drugs. 2014 Sep;25(8):938-49.
