BNC-1 ( BNC-1 | BNC 1 | BNC1 )

产品货号. M16864 CAS No. 96335-59-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BNC-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BNC-1 是一种淀粉样蛋白病理学的小分子调节剂，通过促进 Elk-1 的磷酸化和激活。
产品描述

BNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1, a transcriptional repressor of presenilin-1 but not presenilin-2; increases levels of synaptophysin and synapsin, markers of synaptic integrity, but does not adversely impact presenilin-2 or processing of Notch-1, significantly decreases amyloid burden and improves markers of synaptic integrity in a well-established mouse model of amyloid deposition.
体外实验

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体内实验

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同义词

BNC-1 | BNC 1 | BNC1
通路

Others
靶点

Amyloids
受体

Amyloids
研究领域

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适应症

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CAS Number

96335-59-0
分子量

282.299
分子式

C16H14N2O3
纯度

>98% (HPLC)
溶解度

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SMILES

O=C(C(C(C)=NC(C)=C12)=C2C3=CC=CC=C3NC1=O)OC
化学全称

Methyl 2,4-dimethyl-5-oxo-5,6-dihydrobenzo[c][2,7]naphthyridine-1-carboxylate