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Artemisitene
CAS No. 101020-89-7
Artemisitene ( —— )
产品货号. M23216 CAS No. 101020-89-7
青蒿素是青蒿素的氧化形式，是一种抗疟药。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1596 | 有现货 |
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| 10MG | ￥2811 | 有现货 |
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| 25MG | ￥4771 | 有现货 |
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| 50MG | ￥6820 | 有现货 |
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| 100MG | ￥9396 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Artemisitene
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述青蒿素是青蒿素的氧化形式，是一种抗疟药。
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产品描述Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisinic acid, etc.
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体外实验Artemisitene selectively induces DNA double-stranded breaks (DSBs) and apoptosis in various human cancer cells by suppressing the expression of topoisomerases in human cancer cells. Artemisitene selectively destabilizes c-Myc in human cancer cells by promoting the ubiquitination of c-Myc through the specific induction of the c-Myc E3 ligase NEDD4.
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体内实验In Nrf2 wild-type mice, systemic administration of Artemisitene (5-10 mg/kg; i.p.) strongly inhibits bleomycin-induced lung damage.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number101020-89-7
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分子量280.32
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分子式C15H20O5
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纯度>98% (HPLC)
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溶解度DMSO:Soluble
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SMILESC[C@H](CCC1C2=C)[C@H](CC3)[C@]11OO[C@@]3(C)O[C@H]1OC2=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Li Y, Wu YL. An over four millennium story behind qinghaosu (artemisinin)--a fantastic antimalarial drug from a traditional chinese herb. Curr Med Chem. 2003 Nov;10(21):2197-230.
