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AZ194
CAS No. 2241651-99-8
AZ194 ( CRMP2-Ubc9-NaV1.7 inhibitor 194 )
产品货号. M28702 CAS No. 2241651-99-8
CRMP2-Ubc9-NaV1.7 抑制剂 194 是一种 CRMP2-Ubc9-NaV1.7 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1442 | 有现货 |
|
| 10MG | ￥2341 | 有现货 |
|
| 25MG | ￥4358 | 有现货 |
|
| 50MG | ￥6302 | 有现货 |
|
| 100MG | ￥8829 | 有现货 |
|
| 500MG | ￥17658 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AZ194
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CRMP2-Ubc9-NaV1.7 抑制剂 194 是一种 CRMP2-Ubc9-NaV1.7 抑制剂。
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产品描述CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
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体外实验——
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体内实验AZ194 would provide pain relief in rat models of chemotherapy- and nerve injury- induced neuropathic pain. AZ194 (orally; at 2 and 10 mg/kg) restores mechanical sensitivity in animals with chemotherapy-induced and nerve injury-induced neuropathic nociception.AZ194 (10 mg/kg; ip; CD1 male mice) does not affect motor performance (open field). AZ194 synergizes with commonly used painkillers, engages NaV1.7-dependent endogenous opioid signaling.
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同义词CRMP2-Ubc9-NaV1.7 inhibitor 194
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number2241651-99-8
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分子量567.637
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分子式C34H31F2N3O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 33.33 mg/mL (58.72 mM)
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SMILESCOc1cc(ccc1OCc1cccc(F)c1)C(=O)N1CCC(CC1)c1nc2ccccc2n1Cc1cccc(F)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Dzierba CD, Hartz RA, Bronson JJ. Recent advances in corticotropin-releasing factor receptor antagonists. Annu Rep Med Chem. 2008;43:3–23.
产品手册
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