AZ-1355

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

AZ-1355 是一种有效的降脂药，并能够抑制体内血小板凝集，提高体外前列腺素 I2/血栓素A2 的比例。

AZ-1355 is an effctive lipid-lowering compound, which also inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.

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AZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rat. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats. AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice.

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GPCR/G Protein

Prostaglandin Receptor

Prostaglandin Receptor

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75451-07-9

299.32

C17H17NO4

>98% (HPLC)

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O(C)C1=C2C(CNC=3C(O2)=CC=C(C(OCC)=O)C3)=CC=C1

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(-20℃)

With Ice Pack

≥ 2 years