ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicity of the mutant androgen receptor (AR) responsible for SBMA in cell, fly and mouse models. Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap ‘n’ collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies.

琥珀酸依替尼是一种口服活性选择性表皮生长因子受体酪氨酸激酶抑制剂 (EGFR-TKI)，旨在实现最佳的脑渗透。琥珀酸依替尼可用于癌症研究。

牛磺鹅去氧胆酸是动物胆汁酸的主要生物活性物质之一。