4-Methylcatechol
CAS No. 452-86-8
4-Methylcatechol ( p-Methylcatechol | 34-Dihydroxytoluene | Homocatechol | 4-methylbenzene-12-diol )
产品货号. M19606 CAS No. 452-86-8
4-甲基儿茶酚是高原儿茶酸的代谢产物。它既是儿茶酚 2,3-双加氧酶的底物又是自杀抑制剂。已知 4-甲基儿茶酚可诱导脑源性神经营养因子 (BDNF) 的产生。最近的研究表明,边缘系统中缺乏脑源性神经营养因子(BDNF)可能会导致神经性疼痛。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 200MG | 获取报价 | 有现货 |
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生物学信息
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产品名称4-Methylcatechol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述4-甲基儿茶酚是高原儿茶酸的代谢产物。它既是儿茶酚 2,3-双加氧酶的底物又是自杀抑制剂。已知 4-甲基儿茶酚可诱导脑源性神经营养因子 (BDNF) 的产生。最近的研究表明,边缘系统中缺乏脑源性神经营养因子(BDNF)可能会导致神经性疼痛。
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产品描述4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
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体外实验——
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体内实验——
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同义词p-Methylcatechol | 34-Dihydroxytoluene | Homocatechol | 4-methylbenzene-12-diol
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通路Others
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靶点Other Targets
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受体Catechol 23-Dioxygenase
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研究领域Neurological Disease
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适应症Diabetic neuropathies; Neuropathic pain
化学信息
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CAS Number452-86-8
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分子量124.14
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分子式C7H8O2
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM;Water: Soluble;Ethanol: Soluble
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SMILESCc1ccc(O)c(O)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Okuta A et al. Construction of chimeric catechol 23-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70(3):1804-10.
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