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3-Hydroxykynurenine
CAS No. 484-78-6
3-Hydroxykynurenine ( —— )
产品货号. M34973 CAS No. 484-78-6
3-Hydroxykynurenine 是一种色氨酸代谢物，是潜在的内源性神经毒素，在几种神经退行性疾病中表达水平都有升高的现象。3-Hydroxykynurenine 诱导神经细胞凋亡 (apoptosis)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥646 | 有现货 |
|
| 5MG | ￥961 | 有现货 |
|
| 10MG | ￥1478 | 有现货 |
|
| 25MG | ￥2714 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称3-Hydroxykynurenine
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述3-Hydroxykynurenine 是一种色氨酸代谢物，是潜在的内源性神经毒素，在几种神经退行性疾病中表达水平都有升高的现象。3-Hydroxykynurenine 诱导神经细胞凋亡 (apoptosis)。
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产品描述3-Hydroxykynurenine, a?metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis.
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体外实验Cell Proliferation Assay Cell Line:CD3/CD28 bead-stimulated CD4+?T cells Concentration:0, 20, 40, 60, 80, and 100 μM Incubation Time:72 hours Result:Significantly inhibited CD4+?T-cell proliferation in a dose-dependent manner with an IC50?of approximately 70 μM.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number484-78-6
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分子量224.21
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分子式C10H12N2O4
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纯度>98% (HPLC)
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溶解度In Vitro:?1M HCl 中的溶解度 : 33.33 mg/mL (148.66 mM; 超声助溶 酸性条件溶解 (HCL 调节，pH≈1))
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SMILESNC(CC(=O)c1cccc(O)c1N)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. S Okuda,?et al. 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity. J Neurochem.?1998 Jan;70(1):299-307.?
产品手册
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