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2-Hydroxy-1,7,8-trimethoxy-3-methyl-9,10-anthracenedione
CAS No. 2195434-05-8
2-Hydroxy-1,7,8-trimethoxy-3-methyl-9,10-anthracenedione ( 1,7,8-三甲氧基-2-羟基-3-甲基-蒽醌 )
产品货号. M38228 CAS No. 2195434-05-8
OAT1/3-IN-2 (compound 8) 是 OAT1 和 OAT3 的双抑制剂。OAT1/3-IN-2 可逆转 Cys-Hg 对 HEK-OAT1 细胞的毒性 (10 μM)，对肾脏具有潜在保护作用。OAT1/3-IN-2 可用于研究汞引起的肾损伤。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | 获取报价 | 有现货 |
|
| 50MG | 获取报价 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称2-Hydroxy-1,7,8-trimethoxy-3-methyl-9,10-anthracenedione
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述OAT1/3-IN-2 (compound 8) 是 OAT1 和 OAT3 的双抑制剂。OAT1/3-IN-2 可逆转 Cys-Hg 对 HEK-OAT1 细胞的毒性 (10 μM)，对肾脏具有潜在保护作用。OAT1/3-IN-2 可用于研究汞引起的肾损伤。
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产品描述OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage.
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体外实验———
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体内实验———
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同义词1,7,8-三甲氧基-2-羟基-3-甲基-蒽醌
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通路Others
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靶点Other Targets
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受体Organic anion transporter 1 and 3 (OAT1 and OAT3)
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研究领域———
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适应症———
化学信息
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CAS Number2195434-05-8
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分子量328.32
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分子式C18H16O6
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纯度>98% (HPLC)
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溶解度———
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Wang X, et al. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity. Toxicol Sci. 2018 Feb 1;161(2):321-334.?2.
产品手册
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